His career-long focus has been on providing the highest level of expert, multi-systems care and optimizing the health and well-being of children and adults. Jeff is recognized as a leading educator of patients and health professionals at Harvard Medical School and MGH. He completed a fellowship in Musculoskeletal and Sports Medicine at Boston University/Boston Medical Center, and since 2011, he has practiced sports medicine in the departments of Orthopedics and Pediatrics at Massachusetts General Hospital. Jeffrey Kreher, wellstead health's chief medical officer, received his MD from the University of Missouri-Columbia Medical School and did his residency in adult and pediatric medicine at Indiana University, where he served as Chief Resident. Kreher, MD, FAAP, IFMCPDr.Jeffery Kreherĭr. Recent studies about the microbiome lactate production/utilization (example(s) from GI effects Use of lactate as a metabolic fitness marker (potential applications of Metabolomix+ to infer areas of education/treatment) However, the microbiome utilization of lactate in athletes, specifically by Veillonella atypica, is furthering our understanding of systems biology of metabolic health.įunctional medicine testing highlights the changes in exercise metabolomics to guide management and education of patients through movement recommendations. Lactate metabolism is tightly regulated and recognized by many as a marker of metabolic health. Furthermore, recent developments in microbiome research have highlighted lactate's role in exercise performance and metabolism. Microbiome analyses of athletes generally confirm beneficial effects of exercise mechanistically through changes in the gut microbiome. Recent application of microbiome analysis and metabolomics can help further understanding of metabolic health including the benefit of applying movement to chronic metabolic conditions. "Sportomics" works to advance knowledge in integrative physiology and the systems biology of movement with a goal to translate markers associated with metabolic challenges of training/competition to similar stresses of disease settings. "Sportomics" applies metabolomics to investigate the metabolic effects of physical exercise on individuals. Sportomics, Metabolic Health, and Utilization of Functional Medicine Testing Abnormal values suggesting intestinal dysbiosis, food allergy, parasite infection, exocrine pancreatic insufficiency, or gastrointestinal inflammatory processes were the most common findings. In a retrospective database review study of subjects with IBS-like symptoms, a large proportion (more than 80%) were found to have potentially treatable conditions that produced the IBS-like symptoms. A positive result on one or more fecal biomarker tests may guide therapy, either by suggesting a treatable alternative diagnosis or by eliminating a diagnosis from further consideration, allowing resources to be redirected to more likely diagnoses.īelow are links to IBS population studies utilizing Genova stool testing that demonstrate clinical utility and cost-effectiveness. Fecal biomarker testing has the advantage of permitting multiple tests, in parallel, on a single specimen. Many of the treatable conditions capable of producing symptoms that meet Rome criteria for IBS can be detected or suggested by evaluation of selected biomarkers that appear in fecal material. Gut Health Irritable Bowel Syndrome (IBS) These cases highlight the need to treat the underlying cause when follow up tests do not show improvement. Testing nuances are discussed, including collecting off schedule and a poor quality sample. This module features two patients who had an initial and a follow up SIBO breath test. The patient cases include a patient who has already had SIBO treatment, and another patient who has results from a GI Effects Comprehensive Stool profile with treatment considerations. This module covers two cases that incorporate testing nuances, such as collecting off schedule, and how to interpret an elevated baseline finding. This module is appropriate for a practitioner that is new to Genova's SIBO breath test. There is a general overview of the SIBO report itself, followed by a case study. In this module you will learn how to interpret the SIBO breath test. Each video includes in-depth case study reviews. Learn to interpret our Small Intestinal Bacterial Overgrowth (SIBO) breath test with interpretive videos for beginner and advanced users. Gut Health Interpreting the SIBO Breath Test
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